BDBM50542383 CHEMBL4643729

SMILES COC(=O)C1CCCN(Cc2ccc3nc4C(=O)c5cc(F)ccc5-n4c(=O)c3c2)C1

InChI Key InChIKey=KIGHWMYCRYPNLO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50542383   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Tongji University

Curated by ChEMBL
LigandPNGBDBM50542383(CHEMBL4643729)
Affinity DataIC50: 1.43E+3nMAssay Description:Inhibition of IDO1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Tongji University

Curated by ChEMBL
LigandPNGBDBM50542383(CHEMBL4643729)
Affinity DataIC50: 370nMAssay Description:Inhibition of IDO1 in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Tongji University

Curated by ChEMBL
LigandPNGBDBM50542383(CHEMBL4643729)
Affinity DataIC50: 2.87E+3nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli BL21 using L-Trp as substrate incubated for 30 mins by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed