BDBM50542315 CHEMBL4642428

SMILES CC[C@@](O)(c1cn(nn1)C(C)c1ccc2c(cc(nc2c1)C(N)=O)-c1ccc(F)cc1)C(F)(F)F

InChI Key InChIKey=SJIFJFPZDNDEGR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50542315   

TargetMetabotropic glutamate receptor 2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50542315(CHEMBL4642428)
Affinity DataIC50: 12nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50542315(CHEMBL4642428)
Affinity DataIC50: 12nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50542315(CHEMBL4642428)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human mGluR3 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50542315(CHEMBL4642428)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human mGluR3 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed