BDBM50542313 CHEMBL4637618

SMILES CC[C@@](O)(c1cnn(Cc2ccc3c(cc(nc3c2)C(N)=O)-c2ccc(F)cc2)c1)C(F)(F)F

InChI Key InChIKey=KJVRSANDCLPFGO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50542313   

TargetMetabotropic glutamate receptor 2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50542313(CHEMBL4637618)
Affinity DataIC50: 10nMAssay Description:Negative allosteric modulation of human mGluR2 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50542313(CHEMBL4637618)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human mGluR3 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed