BDBM50542273 CHEMBL4159153

SMILES OC(=O)[C@H]1CCC[C@H]1C(=O)N1CCc2ccccc2[C@H]1CN1C(=O)c2ccccc2C1=O

InChI Key InChIKey=VLYHLCQLLVPWJM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50542273   

TargetKelch-like ECH-associated protein 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50542273(CHEMBL4159153)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of KEAP1 interaction with Nrf2 (unknown origin) by SRP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50542273(CHEMBL4159153)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of KEAP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed