BDBM50542210 CHEMBL4638377

SMILES CC(C)(C)c1cccc(c1)C(=O)Nc1ccc(cc1)C(=O)NO

InChI Key InChIKey=JPPULHHJZRLITK-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50542210   

TargetHistone deacetylase 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542210(CHEMBL4638377)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of C-terminal His-tagged and N-terminal GST-tagged full length human HDAC3 expressed in baculovirus expression system co-expressed with hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542210(CHEMBL4638377)
Affinity DataIC50: 66nMAssay Description:Inhibition of C-terminal FLAG-tagged full length human HDAC6 expressed in baculovirus expression system using FAM-RHKK(Ac)-NH2 substrate incubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542210(CHEMBL4638377)
Affinity DataIC50: 34nMAssay Description:Inhibition of N-terminal His-tagged full length human HDAC8 expressed in baculovirus expression system using FAM-RHKK(TF-Ac)-NH2 substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542210(CHEMBL4638377)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal His-tagged full length human HDAC11 expressed in baculovirus expression system using FAM-RHKK(TF-Ac)-NH2 substrate incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542210(CHEMBL4638377)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length human HDAC3 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Electr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542210(CHEMBL4638377)
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant full length human HDAC6 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Electr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542210(CHEMBL4638377)
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant full length human HDAC8 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Electr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50542210(CHEMBL4638377)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length human HDAC11 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed