BDBM50542062 CHEMBL4634494

SMILES Cc1noc(n1)-c1ccc(OCCN2CC[C@H](C2)C(C(N)=O)(c2ccccc2)c2ccccc2)cc1

InChI Key InChIKey=FLWHTSWTIAIEHT-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50542062   

TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542062(CHEMBL4634494)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human CXCR7 receptor expressed in CHOK1 cell membranes assessed as increase in beta-arrestin recruitment incubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542062(CHEMBL4634494)
Affinity DataKi:  1.17E+4nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 receptor expressed in CHOK1 cell membranes incubated for 2 hrs by radiolabeled ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetAtypical chemokine receptor 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50542062(CHEMBL4634494)
Affinity DataKi:  1.18E+4nMAssay Description:Displacement of [125I]-CXCL12 from human CXCR7 receptor expressed in CHOK1 cell membranes incubated for 2 hrs by radiolabeled ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed