BDBM50541821 CHEMBL4639892

SMILES Nc1ccnc2c(cccc12)C(=O)NC1CCC(=O)NC1=O

InChI Key InChIKey=UGROCUUBWRTGOP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50541821   

TargetBromodomain-containing protein 4(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50541821(CHEMBL4639892)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of BRD4 bromodomain 2 (unknown origin) in HEK293 cells cotransfected with eGFP by flow cytometry based mCherry reporter gene analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetProtein cereblon(Human)
Usona Institute

Curated by ChEMBL
LigandPNGBDBM50541821(CHEMBL4639892)
Affinity DataKi:  2.20E+3nMAssay Description:Binding affinity to CBRN (unknown origin) incubated for 60 mins by lenalidomide displacement assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed