BDBM50541679 CHEMBL4647465

SMILES CN(C)c1cccc(c1)-c1c(F)cc(cc1F)-n1nnc2c1C(=O)c1ccccc1C2=O

InChI Key InChIKey=DIQAKQHNMJSKDT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50541679   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50541679(CHEMBL4647465)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human DHODH using dihydroorotate as substrate and CoQ10 as co-substrate preincubated for 30 mins followed by substrate addition by DCIP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed