BDBM50541502 CHEMBL4303296

SMILES CN1CCN(CC1)C(=O)CN[C@@H]1C[C@H]1c1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=YAMSXCOVJUUMCT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50541502   

TargetLysine-specific histone demethylase 1A(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50541502(CHEMBL4303296)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/13/2021
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50541502(CHEMBL4303296)
Affinity DataIC50: 70nMAssay Description:Inhibition of N-terminal GST-tagged human LSD1 (158 to end residues) expressed in Escherichia coli using (NH2-ARTK(me2)-QTARKSTGGKAPRKQKA-COOH as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50541502(CHEMBL4303296)
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal GST-tagged human LSD1 (158 to end residues) expressed in Escherichia coli using biotinylated H3K4Me2 peptide as substrate pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 1A(Human)
Liaocheng University

Curated by ChEMBL
LigandPNGBDBM50541502(CHEMBL4303296)
Affinity DataIC50: 20nMAssay Description:Inhibition of N-terminal GST-tagged human LSD1 (158 to end residues) expressed in Escherichia coli using (NH2-ARTK(me2)-QTARKSTGGKAPRKQKA-COOH as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50541502(CHEMBL4303296)
Affinity DataIC50: 510nMAssay Description:Inhibition of MAO-A (unknown origin) measured after 60 mins by luciferin-based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Key Laboratory of Henan Provinc

Curated by ChEMBL
LigandPNGBDBM50541502(CHEMBL4303296)
Affinity DataIC50: 2.79E+3nMAssay Description:Inhibition of MAO-B (unknown origin) measured after 60 mins by luciferin-based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed