BDBM50541262 6-Formylindolo[3,2-B]Carbazole::CHEMBL472031

SMILES c1ccc2c(c1)c3cc4c(c5ccccc5[nH]4)c(c3[nH]2)C=O

InChI Key InChIKey=ZUDXFBWDXVNRKF-UHFFFAOYSA-N

Data  1 Kd  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50541262   

TargetAryl hydrocarbon receptor(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50541262(6-Formylindolo[3,2-B]Carbazole | CHEMBL472031)
Affinity DataEC50:  2nMAssay Description:Agonist activity at AhR in human HepG2 cells assessed as induction of CYP1A1 expression after 24 hrs by ethoxyresorufin-O-deethylase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50541262(6-Formylindolo[3,2-B]Carbazole | CHEMBL472031)
Affinity DataEC50:  9.06E+3nMAssay Description:Agonist activity at AhR in human HepG2 cells assessed as induction of AhR transcriptional activity incubated for 24 hrs by Quanti-Luc reagent based l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetAryl hydrocarbon receptor(Human)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50541262(6-Formylindolo[3,2-B]Carbazole | CHEMBL472031)
Affinity DataKd:  70nMAssay Description:Binding affinity to AhR (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed