BDBM50541110 CHEMBL522613

SMILES Cc1ccc2oc(nc2c1)-c1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=OTMXSZCCSFYOKJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50541110   

Target72 kDa type IV collagenase(Human)
"A. Moro" University of Bari

Curated by ChEMBL
LigandPNGBDBM50541110(CHEMBL522613)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of recombinant human MMP2 catalytic domain (Tyr110 to Asp452 residues) expressed in yeast cells using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2/...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
"A. Moro" University of Bari

Curated by ChEMBL
LigandPNGBDBM50541110(CHEMBL522613)
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of recombinant human MMP8 catalytic domain (Phe99 to Gln269 residues) expressed in Escherichia coli cells using Mca-Pro-Leu-Gly-Leu-Dpa-Al...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
"A. Moro" University of Bari

Curated by ChEMBL
LigandPNGBDBM50541110(CHEMBL522613)
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of recombinant human MMP9 catalytic domain (Phe107 to Pro449 residues) expressed in Escherichia coli cells using Mca-Pro-Leu-Gly-Leu-Dpa-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCollagenase 3(Human)
"A. Moro" University of Bari

Curated by ChEMBL
LigandPNGBDBM50541110(CHEMBL522613)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of recombinant human MMP13 catalytic domain (Tyr104 to Asn274 residues) expressed in Escherichia coli cells using Mca-Pro-Leu-Gly-Leu-Dpa-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed