BDBM50541071 CHEMBL4528766

SMILES CN(CC#C)c1nc(NCCCCC2CCN(Cc3ccccc3)CC2)c(cc1C#N)C#N

InChI Key InChIKey=WCDDKWWOUYHUDU-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50541071   

TargetAcetylcholinesterase(Electric eel)
Universidade De Lisboa

Curated by ChEMBL
LigandPNGBDBM50541071(CHEMBL4528766)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Universidade De Lisboa

Curated by ChEMBL
LigandPNGBDBM50541071(CHEMBL4528766)
Affinity DataIC50: 3.95E+3nMAssay Description:Inhibition of human MAO BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Universidade De Lisboa

Curated by ChEMBL
LigandPNGBDBM50541071(CHEMBL4528766)
Affinity DataIC50: 600nMAssay Description:Inhibition of equine serum BuChE by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Universidade De Lisboa

Curated by ChEMBL
LigandPNGBDBM50541071(CHEMBL4528766)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Universidade De Lisboa

Curated by ChEMBL
LigandPNGBDBM50541071(CHEMBL4528766)
Affinity DataIC50: 600nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
St. John'S University

Curated by ChEMBL
LigandPNGBDBM50541071(CHEMBL4528766)
Affinity DataIC50: 100nMAssay Description:Inhibition of human MAO-A using Tyramine hydrochloride as substrate preincubated for 30 mins followed by substrate addition and measured for 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Universidade De Lisboa

Curated by ChEMBL
LigandPNGBDBM50541071(CHEMBL4528766)
Affinity DataIC50: 3.95E+3nMAssay Description:Inhibition of human MAO-B using Tyramine hydrochloride as substrate preincubated for 30 mins followed by substrate addition and measured for 1 hr by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed