BDBM50541002 CHEMBL4642420::US12017994, Ref #20'

SMILES Cc1cc(C)c2[nH]c(=O)c(CN(CCO)C(=O)Nc3ccccc3C)cc2c1

InChI Key InChIKey=XXZCUMSTLDGVBM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50541002   

TargetBeta-glucuronidase(Human)
University of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50541002(CHEMBL4642420 | US12017994, Ref #20')
Affinity DataIC50: 118nMAssay Description:Inhibition of beta-glucuronidase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetBeta-glucuronidase(Escherichia coli (strain K12))
Symberix

US Patent
LigandPNGBDBM50541002(CHEMBL4642420 | US12017994, Ref #20')
Affinity DataIC50: 118nMAssay Description:Successful drug candidate compounds were subjected to numerous biochemical and cellular assays. Purified bacterial β-glucuronidases were challen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2024
Entry Details
Go to US Patent