BDBM50541 (6Z)-6-[(2,5-dimethyl-1H-indol-3-yl)methylene]-5-imino-3-(isopropylsulfonyl)-5,6-dihydro-7H-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one::5-amino-6-[(Z)-(2,5-dimethyl-3-indolylidene)methyl]-3-propan-2-ylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one::5-amino-6-[(Z)-(2,5-dimethylindol-3-ylidene)methyl]-3-isopropylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one::5-amino-6-[(Z)-(2,5-dimethylindol-3-ylidene)methyl]-3-propan-2-ylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one::5-azanyl-6-[(Z)-(2,5-dimethylindol-3-ylidene)methyl]-3-propan-2-ylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one::MLS000730746::SMR000309121::cid_16195591

SMILES CC(C)S(=O)(=O)c1nsc2nc(=O)c(\C=C3/C(C)=Nc4ccc(C)cc34)c(N)n12

InChI Key InChIKey=HMYMFQKRUOWPJR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50541   

TargetM17 leucyl aminopeptidase(Plasmodium falciparum (isolate 3D7))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM50541(5-azanyl-6-[(Z)-(2,5-dimethylindol-3-ylidene)methy...)
Affinity DataIC50: 7.16E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2011
Entry Details
PCBioAssay
TargetM1 family aminopeptidase(Plasmodium falciparum (isolate FcB1 / Columbia))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM50541(5-azanyl-6-[(Z)-(2,5-dimethylindol-3-ylidene)methy...)
Affinity DataIC50: 9.85E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2011
Entry Details
PCBioAssay
LigandPNGBDBM50541(5-azanyl-6-[(Z)-(2,5-dimethylindol-3-ylidene)methy...)
Affinity DataIC50: 1.18E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay