BDBM50540150 CHEMBL3559961::US10626094, Example I179::US11220486, Compound I179

SMILES C(CNc1cc(nc2ccccc12)-c1ccccc1)CN1CCOCC1

InChI Key InChIKey=UUCHZVXLNVRFIC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50540150   

TargetCholinesterase(Horse)
Henan University

Curated by ChEMBL
LigandPNGBDBM50540150(CHEMBL3559961 | US11220486, Compound I179 | US1062...)
Affinity DataIC50: 4.44E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Henan University

Curated by ChEMBL
LigandPNGBDBM50540150(CHEMBL3559961 | US11220486, Compound I179 | US1062...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition by Ellman's met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Human)
La Jolla Institute of Allergy & Immunology

US Patent
LigandPNGBDBM50540150(CHEMBL3559961 | US11220486, Compound I179 | US1062...)
Affinity DataIC50: 5.00E+3nMAssay Description:A listing of materials is provided: Item, source, catalog no. LMPTP-A Enzyme Stock Solution (4.22 mg/ml or 206.8 μM), SBMRI Protei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2022
Entry Details
Go to US Patent

TargetPotassium channel subfamily K member 2(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM50540150(CHEMBL3559961 | US11220486, Compound I179 | US1062...)
Affinity DataIC50: 5.00E+3nMAssay Description:1. Prepare Reagents as described in section F. Recipe.2. Using LabCyte Echo, transfer 60 nL from 2 mM test compound source plate into assay plate Col...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2023
Entry Details
Go to US Patent