BDBM50540069 CHEMBL4637826::US11572366, Example 8

SMILES Cc1c(cccc1-c1ccccc1)-c1nc2cc(CNCCO)ccc2o1

InChI Key InChIKey=ZNOWLLPAHTWELC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50540069   

TargetProgrammed cell death 1 ligand 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540069(CHEMBL4637826 | US11572366, Example 8)
Affinity DataIC50: 100nMAssay Description:Antagonist activity against PDL1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50540069(CHEMBL4637826 | US11572366, Example 8)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PD-1/PD-L1 interaction (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
LigandPNGBDBM50540069(CHEMBL4637826 | US11572366, Example 8)
Affinity DataIC50: 10nMAssay Description:Inhibitors were first serially diluted in DMSO and then added to the plate wells before the addition of other reaction components. The final concentr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2023
Entry Details
Go to US Patent

TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540069(CHEMBL4637826 | US11572366, Example 8)
Affinity DataIC50: 10nMAssay Description:Inhibition of human PD-1/PD-L1 interactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed