BDBM50540065 CHEMBL4645487::US11718605, Example 1

SMILES Cc1c(NC(=O)c2cc(CN3CCCC[C@H]3C(O)=O)cn(C)c2=O)cccc1-c1ccccc1

InChI Key InChIKey=DNPQQJGPLXEEDA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50540065   

TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540065(CHEMBL4645487 | US11718605, Example 1)
Affinity DataIC50: 100nMAssay Description:Inhibition of human PD1/PDL1 protein-protein interaction by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50540065(CHEMBL4645487 | US11718605, Example 1)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human PD-1/PD-L1 interaction incubated for 40 mins by HTRF binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
LigandPNGBDBM50540065(CHEMBL4645487 | US11718605, Example 1)
Affinity DataIC50: 100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
Go to US Patent