BDBM50540040 CHEMBL4640793

SMILES C[C@@H](Nc1nc2n(ncc2c(=O)n1Cc1ccccc1)C(C)(C)C)c1ccc(Cl)cc1

InChI Key InChIKey=LXNGGQJZNQYUJZ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50540040   

TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50540040(CHEMBL4640793)Copy SMILESCopy InChI

Affinity DataIC50: 1.5nMAssay Description:Inhibition of PDE1C2 (147 to 531 residues) (unknown origin) using [3H]-cGMP substrate incubated for 15 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/12/2021
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C(Human)
Sun Yat-Sen University

Curated by ChEMBL

LigandBDBM50540040(CHEMBL4640793)Copy SMILESCopy InChI

Affinity DataIC50: 1.5nMAssay Description:Inhibition of PDE1C (unknown origin)More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/18/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL