BDBM50539784 CHEMBL1096940

SMILES [#6]-[#8]-c1cc(-[#8])c(cc1-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](\[#6])-[#6])-[#6@@H]-1-[#6]-[#6](=O)-c2c(-[#8])cc(-[#8])cc2-[#8]-1

InChI Key InChIKey=YGCVNMMPVKPHNX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50539784   

TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rabbit)
Centre of Experimental Medicine

Curated by ChEMBL
LigandPNGBDBM50539784(CHEMBL1096940)
Affinity DataIC50: 3.56E+4nMAssay Description:Inhibition of SERCA1 in NewZealand rabbit skeletal muscle SR vesicles using ATP as substrate incubated for 2 mins followed by Ca2+ addition by NADH c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rat)
Centre of Experimental Medicine

Curated by ChEMBL
LigandPNGBDBM50539784(CHEMBL1096940)
Affinity DataIC50: 6.48E+4nMAssay Description:Inhibition of SERCA1 in rat INS-1E cells assessed as reduction in cell viability incubated for 24 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed