BDBM50539691 CHEMBL4642179

SMILES CCOc1cc(Cl)c(cc1N1CCOCC1)C(=O)Nc1nc2ccc(CN3CCN(C)CC3)cc2s1

InChI Key InChIKey=OFCNWKRWXKFYNW-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50539691   

TargetHydroxycarboxylic acid receptor 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50539691(CHEMBL4642179)
Affinity DataEC50:  410nMAssay Description:Agonist activity at human GPR81 overexpressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50539691(CHEMBL4642179)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [125I]-ghrelin from human GHS-R1a stably expressed in HEK cell membrane measured after 60 mins by gamma counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50539691(CHEMBL4642179)
Affinity DataEC50: >1.10E+4nMAssay Description:Agonist activity at human GPR109A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed