BDBM50539553 CHEMBL4644995

SMILES CCn1nnc2c(C)c(ccc12)[C@@H]([C@H](C)C(O)=O)c1ccc2CCN(Cc2c1)C(=O)c1c(C)c(C)cc(C)c1C

InChI Key InChIKey=JUBFIKLKLFGJNP-UHFFFAOYSA-N

Data  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50539553   

TargetKelch-like ECH-associated protein 1(Human)
Biogen

Curated by ChEMBL
LigandPNGBDBM50539553(CHEMBL4644995)
Affinity DataKd:  0.0700nMAssay Description:Binding affinity to Keap1 (unknown origin) by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
LigandPNGBDBM50539553(CHEMBL4644995)
Affinity DataEC50:  60nMAssay Description:Induction of Nrf2 nuclear translocation in human U2OS cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed