BDBM50539193 CHEMBL4639432

SMILES Cc1csc(n1)-c1cc(NC(=O)c2ccc(OCc3ccccn3)cc2)c(C)cc1C

InChI Key InChIKey=JRSCPBAQPXXZTE-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50539193   

TargetSmoothened homolog(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50539193(CHEMBL4639432)
Affinity DataEC50:  0.900nMAssay Description:Inhibition of SMO-mediated Hedgehog signaling pathway in mouse C3H10T1/2 cells assessed as reduction in sonic hedgehog-induced osteoblast differentia...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed