BDBM50538919 CHEMBL4633233

SMILES COc1ccc(cc1F)-c1ccc(COC2(CN(C2)C#N)C2CC2)c(F)c1

InChI Key InChIKey=UQNAYFXNZPLVNU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50538919   

TargetN-acylethanolamine-hydrolyzing acid amidase(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50538919(CHEMBL4633233)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50538919(CHEMBL4633233)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human FAAH expressed in Escherichia coli using fluorogenic AAMCA as substrate by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed