BDBM50538731 CHEMBL4634160

SMILES OC(=O)CC[C@@H](NC(=O)Cc1ccc(Br)cc1)C(=O)NCc1ccc(cc1)[N+]([O-])=O

InChI Key InChIKey=TUEDKFNMSFNCII-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50538731   

TargetHistone deacetylase 8(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50538731(CHEMBL4634160)
Affinity DataIC50: 2.89E+3nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50538731(CHEMBL4634160)
Affinity DataIC50: 2.89E+3nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50538731(CHEMBL4634160)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of human MMP2 incubated for 1 hrs followed by chromogenic substrate addition and measured after 30 mins by microplate photometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50538731(CHEMBL4634160)
Affinity DataIC50: 4.83E+3nMAssay Description:Inhibition of human MMP9 incubated for 1 hrs followed by chromogenic substrate addition and measured after 30 mins by microplate photometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed