BDBM50538510 CHEMBL4640989

SMILES COc1ccc(cc1OC)-c1cnn2c(N)c(-c3ccccc3)c(OC3CCNCC3)nc12

InChI Key InChIKey=QZKXRJMVQTZACR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50538510   

TargetKinesin-1 heavy chain/Proto-oncogene tyrosine-protein kinase receptor Ret(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538510(CHEMBL4640989)
Affinity DataIC50: 79nMAssay Description:Inhibition of KIF5B-RET (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetTranscription factor ETV6/Vascular endothelial growth factor receptor 2(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538510(CHEMBL4640989)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of TEL/KDR (unknown origin) transfected in mouse Ba/F3 cells assessed as reduction in cell viability incubated for 48 hrs by brightglo-luc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetCoiled-coil domain-containing protein 6(Human)
The Genomics Institute of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50538510(CHEMBL4640989)
Affinity DataIC50: 160nMAssay Description:Inhibition of CCDC6/RET (unknown origin) transfected in human LC2/ad cells assessed as reduction in cell viability incubated for 6 days by CellTiter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed