BDBM50538411 CHEMBL4646037

SMILES Cc1ccc(cc1)S(=O)(NC(=O)Nc1c2CCCc2cc2CCCc12)=Nc1ccc(F)cc1

InChI Key InChIKey=JGYIIJYXVNGZCA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50538411   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50538411(CHEMBL4646037)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-primed human THP1 cells assessed as reduction in IL-1beta level preincubated for 1 hr followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed