BDBM50538305 CHEMBL4645862

SMILES CS(=O)(=O)c1nc(cn1C2CCCC2)NS(=O)(=O)c3cc(cc(c3O)Cl)Br

InChI Key InChIKey=ZBIVDOJYQHNICX-UHFFFAOYSA-N

Data  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50538305   

TargetWD repeat-containing protein 5(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50538305(CHEMBL4645862)
Affinity DataKd:  100nMAssay Description:Binding affinity to recombinant human His/FLAG-tagged WDR5 (22 to 334 residues) expressed in Escherichia coli expression system using FITC-AHx-SEEEID...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetWD repeat-containing protein 5(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50538305(CHEMBL4645862)
Affinity DataKd:  100nMAssay Description:Binding affinity towards N-terminal 6xHis-SUMO tagged human WDR5 (22 to 334 residues) measured by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMedPDB3D3D Structure (crystal)