BDBM50538189 CHEMBL4635132

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CCCN1C(=O)CNC(C)=O)C(=O)[C@]1(C)CO1

InChI Key InChIKey=QWEBSYDRFXZQMF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50538189   

TargetProteasome subunit beta type-9(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50538189(CHEMBL4635132)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LMP2 in human 20S immunoproteasome using Ac-PAL-AMC as substrate after 1 hr by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50538189(CHEMBL4635132)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Beta1 subunit in human 20S proteasome using Ac-nLPnLD-AMC as substrate after 1 hr by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-8(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50538189(CHEMBL4635132)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LMP7 in human 20S immunoproteasome using Ac-ANW-AMC as substrate after 1 hr by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50538189(CHEMBL4635132)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Beta5 in human 20S immunoproteasome usingAc-WLA-AMC as substrate after 1 hr by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed