BDBM50538172 CHEMBL4634764

SMILES CCc1ccc(C[C@H](NC(=O)[C@@H]2CCCN2C(=O)CNC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]2(C)CO2)cc1

InChI Key InChIKey=QJHFQWXOTMNLEA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50538172   

TargetProteasome subunit beta type-9(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50538172(CHEMBL4634764)
Affinity DataIC50: 134nMAssay Description:Inhibition of LMP2 in human 20S immunoproteasome using Ac-PAL-AMC as substrate after 1 hr by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed