BDBM50538094 CHEMBL4641631

SMILES O=C(NC1CC1)Nc1cc(ccn1)-c1cn(C2CCOCC2)c2cnccc12

InChI Key InChIKey=XYBONUYZXAAEMM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50538094   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50538094(CHEMBL4641631)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50538094(CHEMBL4641631)
Affinity DataIC50: 5.64E+3nMAssay Description:Inhibition of recombinant human His/GST-tagged GSK3beta (2 to 433 residues) expressed in baculovirus infected Sf9 cells using Ulight-glycogen synthas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Genomics Institute of The Novartis Research Foundation (Gnf)

Curated by ChEMBL
LigandPNGBDBM50538094(CHEMBL4641631)
Affinity DataIC50: 4.60E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in CHO cells incubated for 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed