BDBM50537996 CHEMBL4632827

SMILES c1nn2cccnc2c1-c1nc2ccccc2s1

InChI Key InChIKey=SAZAMNXEWSKXHU-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50537996   

TargetTyrosine-protein kinase JAK1(Human)
Brigham Young University

Curated by ChEMBL
LigandPNGBDBM50537996(CHEMBL4632827)
Affinity DataKd:  550nMAssay Description:Binding affinity to wild-type human partial length JAK1 JH2 pseudokinase domain (R537 to D855 residues) expressed in mammalian expression system at 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Brigham Young University

Curated by ChEMBL
LigandPNGBDBM50537996(CHEMBL4632827)
Affinity DataKd:  410nMAssay Description:Binding affinity to wild-type human partial length PIK3C3 (S282 to H879 residues) expressed in mammalian expression system at 10 uM by Kinomescan met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed