BDBM50537990 CHEMBL4644593

SMILES COc1ccccc1Cc1cc(OCCNC(=O)C=C)c2cc([nH]c2c1)-c1n[nH]c2cc(ccc12)C(F)F

InChI Key InChIKey=ZRFYITKWKPSVFW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50537990   

TargetTyrosine-protein kinase ITK/TSK(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50537990(CHEMBL4644593)
Affinity DataIC50: 32nMAssay Description:Inhibition of ITK (unknown origin) using TK as substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50537990(CHEMBL4644593)
Affinity DataIC50: 187nMAssay Description:Inhibition of BTK (unknown origin) using TK as substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed