BDBM50537989 CHEMBL4642453

SMILES Cc1cccc(Cc2cc(OCCNC(=O)C=C)c3cc([nH]c3c2)-c2n[nH]c3cc(ccc23)C(F)F)c1

InChI Key InChIKey=IXJAYHQRMNJRAS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50537989   

TargetTyrosine-protein kinase ITK/TSK(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50537989(CHEMBL4642453)
Affinity DataIC50: 34nMAssay Description:Inhibition of ITK (unknown origin) using TK as substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50537989(CHEMBL4642453)
Affinity DataIC50: 235nMAssay Description:Inhibition of BTK (unknown origin) using TK as substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed