BDBM50537730 CHEMBL4649731::US11230547, Compound 3-4

SMILES Cn1cc(cn1)-c1ncc(C#N)c(n1)N1CC2CCC(C1)N2c1cccc(F)c1

InChI Key InChIKey=BASGXOKNBSTXMA-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50537730   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck

Curated by ChEMBL

LigandBDBM50537730(CHEMBL4649731 | US11230547, Compound 3-4)Copy SMILESCopy InChI

Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of recombinant human full-length N-terminal GST-tagged p110delta/untagged full-length p85alpha expressed in baculovirus infected Sf21 cell...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/11/2021
Entry Details Article
Copy Entry DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Merck Sharp & Dohme

US Patent

LigandBDBM50537730(CHEMBL4649731 | US11230547, Compound 3-4)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+3nMAssay Description:This assay was developed and further optimized from a kit produced by Upstate (Millipore catalog #33-047) (Millipore Sigma, Billerica Mass., USA) and...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
5/30/2022
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL