BDBM50537422 CHEMBL4584430

SMILES CCC(=O)N1CCC(CC1)c1ccc(Nc2cc(NCc3cccc(c3)-c3ccncc3)c(cn2)C(N)=O)cc1

InChI Key InChIKey=PTFOMCGWFFJGPW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50537422   

TargetTyrosine-protein kinase JAK3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50537422(CHEMBL4584430)
Affinity DataIC50: 1nMAssay Description:Inhibition of human GST-tagged JAK3 using FITC-KGGEEEEYFELVKK as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50537422(CHEMBL4584430)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human GST-tagged JAK2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50537422(CHEMBL4584430)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human GST-tagged JAK1 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed