BDBM50537183 CHEMBL4575859

SMILES COc1ncccc1C(O)(CCN(C)C)C(c1cccc(C)c1)c1cc2cc(ccc2nc1OC)C#N

InChI Key InChIKey=FHJFOPAQVGZAKG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50537183   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50537183(CHEMBL4575859)
Affinity DataIC50: 300nMAssay Description:Inhibition of human ERG by manual patch clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50537183(CHEMBL4575859)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed