BDBM50537143 CHEMBL4588202

SMILES CCC(=O)N1CCC[C@H](C1)n1nc(-c2cn(nn2)-c2ccc(cc2)C(C)=O)c2c(N)ncnc12

InChI Key InChIKey=DMPCFHLMZNTFEB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50537143   

TargetEpidermal growth factor receptor(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50537143(CHEMBL4588202)
Affinity DataIC50: 677nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50537143(CHEMBL4588202)
Affinity DataIC50: 649nMAssay Description:Inhibition of wild type EGFR (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed