BDBM50537142 CHEMBL4581088

SMILES CC(=O)c1ccc(cc1)-n1cc(nn1)-c1nn([C@@H]2CCCN(C2)C(=O)C=C)c2ncnc(N)c12

InChI Key InChIKey=CKAJNPCKXKPZBT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50537142   

TargetEpidermal growth factor receptor(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50537142(CHEMBL4581088)
Affinity DataIC50: 8.01E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50537142(CHEMBL4581088)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed