BDBM50537131 CHEMBL4575895

SMILES COc1cc(cc(c1OC)OC)Nc2ccnc3c2ccc(c3)C#N

InChI Key InChIKey=BLWQIEISIMYCHD-UHFFFAOYSA-N

Data  5 Kd

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50537131   

TargetAtypical kinase COQ8A, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50537131(CHEMBL4575895)
Affinity DataKd:  66nMAssay Description:Binding affinity to biotinylated full length human ADCK3 expressed in Escherichia coli incubated for 1.5 hrs by fluorescent tracer dependent TR-FRET ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-G-associated kinase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50537131(CHEMBL4575895)
Affinity DataKd:  9.70nMAssay Description:Binding affinity to biotinylated human GAK (13 to 338 residues) expressed in Escherichia coli incubated for 1.5 hrs by fluorescent tracer dependent T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase NLK(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50537131(CHEMBL4575895)
Affinity DataKd:  28nMAssay Description:Binding affinity to biotinylated full length human NLK expressed in Escherichia coli incubated for 1.5 hrs by fluorescent tracer dependent TR-FRET ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50537131(CHEMBL4575895)
Affinity DataKd:  96nMAssay Description:Binding affinity to biotinylated human RIPK2 (1 to 310 residues) expressed in Escherichia coli incubated for 1.5 hrs by fluorescent tracer dependent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetCyclin-G-associated kinase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50537131(CHEMBL4575895)
Affinity DataKd:  43nMAssay Description:Binding affinity to human wild type partial length GAK (G13 to Y338 residues) expressed in bacterial expression system by KinomeScan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed