BDBM50537130 CHEMBL4586530

SMILES COc1ccc2c(Nc3cc(OC)c(OC)c(OC)c3)ccnc2c1

InChI Key InChIKey=GRKVQPWSPUXGKV-UHFFFAOYSA-N

Data  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50537130   

TargetAtypical kinase COQ8A, mitochondrial(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50537130(CHEMBL4586530)
Affinity DataKd:  1.20E+3nMAssay Description:Binding affinity to biotinylated full length human ADCK3 expressed in Escherichia coli incubated for 1.5 hrs by fluorescent tracer dependent TR-FRET ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50537130(CHEMBL4586530)
Affinity DataKd:  200nMAssay Description:Binding affinity to biotinylated human RIPK2 (1 to 310 residues) expressed in Escherichia coli incubated for 1.5 hrs by fluorescent tracer dependent ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetCyclin-G-associated kinase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50537130(CHEMBL4586530)
Affinity DataKd:  17nMAssay Description:Binding affinity to biotinylated human GAK (13 to 338 residues) expressed in Escherichia coli incubated for 1.5 hrs by fluorescent tracer dependent T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase NLK(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50537130(CHEMBL4586530)
Affinity DataKd:  700nMAssay Description:Binding affinity to biotinylated full length human NLK expressed in Escherichia coli incubated for 1.5 hrs by fluorescent tracer dependent TR-FRET ba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetCyclin-G-associated kinase(Human)
Johann Wolfgang Goethe University

Curated by ChEMBL
LigandPNGBDBM50537130(CHEMBL4586530)
Affinity DataKd:  35nMAssay Description:Binding affinity to human wild type partial length GAK (G13 to Y338 residues) expressed in bacterial expression system by KinomeScan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed