BDBM50536941 CHEMBL4521985

SMILES CN(C)CC\C=C1/c2ccccc2COc2ccc(CC(=O)NN)cc12

InChI Key InChIKey=YZOLUQIAJRPDPW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50536941   

TargetPoly [ADP-ribose] polymerase 1(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50536941(CHEMBL4521985)
Affinity DataIC50: 79nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50536941(CHEMBL4521985)
Affinity DataIC50: 79nMAssay Description:Inhibition of human N-terminal His6-tagged PARP1 CD (662 to 1011 residues) expressed in Escherichia coli BL21 incubated for 60 mins by chemiluminesce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50536941(CHEMBL4521985)
Affinity DataIC50: 79nMAssay Description:Inhibition of human recombinant PARP1 incubated for 60 mins by PARP assay kit methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed