BDBM50536939 CHEMBL4569417

SMILES CC(C)(C)[Si](C)(C)OCCCN1CCN(CC1=O)C(=O)c1cc(Cn2c3ccccc3c(=O)[nH]c2=O)ccc1F

InChI Key InChIKey=PVTGCPNFDHKZPA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50536939   

TargetPoly [ADP-ribose] polymerase 2(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50536939(CHEMBL4569417)
Affinity DataIC50: 11nMAssay Description:Inhibition of PARP2 (unknown origin) using histone as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50536939(CHEMBL4569417)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PARP1 (unknown origin) using histone as substrate after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50536939(CHEMBL4569417)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human PARP-1 using histone as substrate incubated for 16 hrs by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50536939(CHEMBL4569417)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human PARP-2 using histone as substrate incubated for 16 hrs by ELISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed