BDBM50536936 CHEMBL4584534

SMILES CNCc1ccc(cc1)-c1cc2cc(F)cc(C(N)=O)c2o1

InChI Key InChIKey=ROBJKLPZIPNAMV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50536936   

TargetPoly [ADP-ribose] polymerase 2(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50536936(CHEMBL4584534)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of PARP2 (unknown origin) by biotinylated NAD+-based luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50536936(CHEMBL4584534)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant human PARP1 using histone as substrate after 1 hr in presence of NAD+ by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50536936(CHEMBL4584534)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Nirma University

Curated by ChEMBL
LigandPNGBDBM50536936(CHEMBL4584534)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of PARP2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed