BDBM50536804 CHEMBL4575488

SMILES C[C@H]1CC[C@H](c2ccc(cc2)C#N)S(=O)(=O)N1Cc1ccc(cc1F)N1CCN(CC1)C(C)=O

InChI Key InChIKey=UJZYLDDRHBCHNK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536804   

TargetNuclear receptor ROR-gamma(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50536804(CHEMBL4575488)
Affinity DataEC50:  3.90E+3nMAssay Description:Inverse agonist activity at human RORc-LBD assessed as inhibition of SRC1 co-activator peptide recruitment by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed