BDBM50536802 CHEMBL4560678

SMILES COc1ccc(cc1)[C@H]1CC[C@H](C)N(Cc2ccc(cc2F)N2CCN(CC2)C(C)=O)S1(=O)=O

InChI Key InChIKey=SLFITVUSWOBPDV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536802   

TargetNuclear receptor ROR-gamma(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50536802(CHEMBL4560678)
Affinity DataEC50:  28nMAssay Description:Inverse agonist activity at human RORc-LBD assessed as inhibition of SRC1 co-activator peptide recruitment by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed