BDBM50536657 CHEMBL4586027

SMILES CSc1ncc(cn1)-c1c(CO)n(Cc2ccccc2Cl)c2cc(OC(F)(F)F)ccc12

InChI Key InChIKey=UBIPFRRCYLLCRN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50536657   

TargetProteinase-activated receptor 4(Human)
Northwest Agriculture & Forestry University

Curated by ChEMBL
LigandPNGBDBM50536657(CHEMBL4586027)
Affinity DataIC50: 210nMAssay Description:Antagonist activity against PAR4 activating peptide domain in human platelets assessed as inhibition of alpha2bbeta3 activation level by PAC1 binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProteinase-activated receptor 4(Human)
Northwest Agriculture & Forestry University

Curated by ChEMBL
LigandPNGBDBM50536657(CHEMBL4586027)
Affinity DataIC50: 204nMAssay Description:Antagonist activity against PAR4 activating peptide domain in human platelets assessed as inhibition of alpha2bbeta3 activation level by PAC1 binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProteinase-activated receptor 1(Human)
Northwest Agriculture & Forestry University

Curated by ChEMBL
LigandPNGBDBM50536657(CHEMBL4586027)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PAR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed