BDBM50536188 CHEMBL4532935

SMILES CCc1nc(N)nc(N)c1C#CC(C)c1cc2OCOc2c(c1)-c1ccncc1

InChI Key InChIKey=BFKKZVMQJNNEFK-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50536188   

TargetDihydrofolate reductase(Escherichia coli (strain K12))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50536188(CHEMBL4532935)
Affinity DataIC50: 39nMAssay Description:Inhibition of Escherichia coli DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50536188(CHEMBL4532935)
Affinity DataIC50: 366nMAssay Description:Inhibition of Escherichia coli DfrA1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50536188(CHEMBL4532935)
Affinity DataKi:  2.5nMAssay Description:Inhibition of TMP/methicillin-resistant Staphylococcus aureus wild type DHFR assessed as oxidation of NADPH pre-incubated for 5 mins followed by dihy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed