BDBM50536186 CHEMBL4483572

SMILES CCc1nc(N)nc(N)c1C#C[C@H](C)c1cc(OC)cc(c1)-c1ccncc1

InChI Key InChIKey=KEPLBUUTAQCZOE-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50536186   

TargetDihydrofolate reductase(Staphylococcus aureus)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50536186(CHEMBL4483572)
Affinity DataIC50: 15nMAssay Description:Inhibition of wild type Staphylococcus aureus DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50536186(CHEMBL4483572)
Affinity DataKi:  2.70nMAssay Description:Inhibition of TMP/methicillin-resistant Staphylococcus aureus wild type DHFR assessed as oxidation of NADPH pre-incubated for 5 mins followed by dihy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed