BDBM50535948 CHEMBL4578266

SMILES Cc1ccc(cc1)-c1nc(NC(=O)C2CCN(Cc3ccc(F)cc3Cl)CC2)sc1-c1ccc(C)cc1

InChI Key InChIKey=FMAFUXOIISRRLB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50535948   

TargetCholinesterase(Horse)
The Maharaja Sayajirao University of Baroda

Curated by ChEMBL
LigandPNGBDBM50535948(CHEMBL4578266)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of equine serum BuChE using BTCI as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by Ellman ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
The Maharaja Sayajirao University of Baroda

Curated by ChEMBL
LigandPNGBDBM50535948(CHEMBL4578266)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human erythrocyte AChE using ATCI as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by Ellman...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed