BDBM50535924 CHEMBL4527101

SMILES COc1ccc(cc1)-c1nc(NC(=O)C2CCN(Cc3ccccc3C(F)(F)F)CC2)sc1-c1ccc(OC)cc1

InChI Key InChIKey=RLYFWJDIVYZVTH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50535924   

TargetCholinesterase(Horse)
The Maharaja Sayajirao University of Baroda

Curated by ChEMBL
LigandPNGBDBM50535924(CHEMBL4527101)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of equine serum BuChE using BTCI as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by Ellman ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
The Maharaja Sayajirao University of Baroda

Curated by ChEMBL
LigandPNGBDBM50535924(CHEMBL4527101)
Affinity DataIC50: 680nMAssay Description:Inhibition of human erythrocyte AChE using ATCI as substrate preincubated for 30 mins followed by substrate addition measured after 30 mins by Ellman...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed